Looksmaxxing › Hairmaxxing
Hairmaxxing
Retention, regrowth, and follicle health.
Hair loss is overwhelmingly driven by DHT-mediated follicle miniaturisation. The good news: it's one of the most thoroughly understood pharmacological problems in the looksmaxxing space.
What it is
Mechanism: 5-alpha reductase converts testosterone into DHT, which binds to follicles and miniaturises them over time. Inhibit 5-AR or block DHT at the follicle and you slow (and often reverse) the process.
Compound classes:
- 5-AR inhibitors (finasteride, dutasteride)
- Topical anti-androgens (RU58841)
- Vasodilators (minoxidil)
- Microneedling protocols
Hair Compounds
9 totalAHK-Cu
Copper Tripeptide
Bimatoprost
Prostamide / PGF2α Analog
Clascoterone
Topical Androgen Receptor Antagonist
Dutasteride
Dual 5α-Reductase Inhibitor
Finasteride
5α-Reductase Inhibitor (Type II/III)
GT20029
Topical AR PROTAC (Androgen Receptor Degrader)
Show 3 more compounds
Minoxidil
K-ATP Channel Opener / Vasodilator
Pyrilutamide
Topical Androgen Receptor Antagonist
RU58841
Topical Androgen Receptor Antagonist
Comparisons
9 totalRU58841 vs Finasteride
Block DHT (and more) directly at the scalp, or suppress it systemically?
Clascoterone vs RU58841
Pharma-grade AR antagonist versus the highest-potency DIY topical for blocking DHT at the follicle.
Bimatoprost vs Minoxidil
Prostaglandin analog for lashes and brows vs. the gold-standard regrowth driver for scalp hair.
RU58841 vs Pyrilutamide
Battle-tested research chem vs. new gold-standard AR antagonist for scalp hair retention.
Pyrilutamide vs Finasteride
Topical AR blockade vs systemic DHT suppression — two very different approaches to hair preservation.
Minoxidil vs Finasteride
Two core hair stack tools — one drives new growth, one blocks the DHT that kills follicles.
Show 3 more comparisons
Clascoterone vs Pyrilutamide
Clinically-backed AR antagonists for hairloss: clascoterone brings regulated safety, pyrilutamide brings raw potency.
Finasteride vs Dutasteride
Finasteride: safer, well-tolerated, and reversible. Dutasteride: heavier DHT suppression, longer half-life, higher potency (and risk).
Minoxidil vs Dutasteride
Minoxidil grows hair. Dutasteride stops miniaturization. Core stack for androgenic hair loss, but entirely different mechanisms.
How to Start
Bloodwork first. If you have a family history of androgenic alopecia and you're noticing thinning, the earlier you intervene, the better the outcome.