Skinmaxx Reset Protocol — Full Acne & Skin Reset | Biomogging

Overview

Skinmaxx Reset is the gold-standard protocol for users who want a definitive, once-and-done reset on oily, acne-prone, or rough skin. It follows the established medical playbook: a full 16-week isotretinoin course for permanent suppression of sebaceous gland activity and deep acne clearance, then transitions to topical tretinoin for long-term collagen remodelling, pigment correction, and maintaining that refined, 'glass skin' look. This stack is for anyone—physique-focused, looksmaxxing, or just tired of chronic breakouts and visible facial oil—seeking results that outclass any cosmetic routine or supplement. If you want the best odds of never fighting severe acne again, there's no better-investigated path.

Why this stack works

Isotretinoin is here as the heavy artillery—no compound can touch its ability to reset oil glands, squash cystic acne, and deliver a permanent shift in skin quality, not just symptom control. Hitting a cumulative 120–150 mg/kg dose over 16 weeks is the only way shown to deliver high rates of true remission, instead of just tamping down breakouts.
Tretinoin phases in as soon as the isotretinoin window ends. Topical tret is the only proven way to keep the anti-acne, pigment-fading, and texture-smoothing gains rolling, and to drive long-term collagen formation for visible anti-aging effects. The cumulative approach knocks out the sebaceous side, and tretinoin keeps cell turnover and skin renewal maxed out for months more.
The two-phase approach leverages isotretinoin's curative hit, then rides out continuous, manageable improvement with tret. No redundancy; just sequencing the best clinical technologies, exactly as top dermatologists do.

Protocol timeline

2 phases · 40 weeks total

Timeline shows the 40-week cycle. Bars overlap when phases run concurrently. Click a bar to jump to its detail card.

Cycle starts

2025

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

2026

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

2027

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

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Dec

Isotretinoin Course

Tretinoin Maintenance

Phase 1

Isotretinoin Course

mainWk 1–1616wk

Isotretinoin

Week	Compound	Dose	Frequency	Notes
1–16	Isotretinoin	0.5–1.0 mg/kg/day	Daily	Take with a fatty meal, same time each day

Bloodwork: Baseline, then repeat at weeks 4, 8, 12, and 16: lipids, AST/ALT, CBC, pregnancy test if applicable.
Vitamin A: Absolutely avoid all other vitamin A/retinol supplements (toxicity risk).
Labs: If triglycerides >3x normal or ALT/AST >2x normal, pause and review.
Sun Protection: Daily SPF 30+ is non-negotiable—photo sensitivity is sharply increased.
Skin Barrier: Use non-comedogenic, ceramide-rich moisturizers twice daily. If lips chap, petrolatum-based balms.
Training: Avoid waxing, laser, or direct joint stress while on—skin fragility and musculoskeletal effects are real.

Phase 2

Tretinoin Maintenance

supportWk 17–4024wk

Tretinoin

Week	Compound	Dose / Strength	Frequency	Notes
17–18	Tretinoin	0.025% cream/gel	2x/week	Start slow: apply at night, sandwich method
19–22	Tretinoin	0.025% cream/gel	Every other night	Ramp up as tolerable
23–40	Tretinoin	0.025–0.05%	Nightly	Maintain; can increase to 0.05% if fully adjusted and irritation-free

Barrier Care: Continue ceramide moisturizer, buffer tretinoin by applying over moisturizer ('sandwich method') for first 4–8 weeks.
SPF: Sun protection remains mandatory every morning.
Adjuncts: Avoid layering harsh actives (AHAs, BHAs, vitamin C serums) over the same skin area until fully tolerized (usually week 8+).
Irritation: If flaking or redness spike, drop to 2x/week until resolved before resuming ramp.

Compounds in this stack

2 linked · tap for full guide

Isotretinoin

Oral Retinoid

Skint½ 10–20 hours (parent); 17–50 hours (4-oxo metabolite)Oral

Tretinoin

Topical Retinoid (RAR Agonist)

Skint½ Local skin effect; systemic plasma t½ ~0.5–2h (negligible after topical dosing)Topical

How they work together

Combined effectiveness

Average 0–10 score per dimension across the compounds in this stack (simple mean per axis).

Same goal as Skinmaxx Reset Protocol

Classic Aesthetic Steroid Blast

High

The textbook 'beach body / photoshoot prep' AAS cycle — testosterone as the base, masteron for the dry hard look and DHT-driven aesthetic, primobolan for lean tissue retention and minimal sides. Aromasin on cycle prevents estrogenic complications, TUDCA covers liver, dual-SERM PCT plus enclomiphene for full hormonal restoration.

16wk7 compoundsPCTView

Aesthetic Lean Bulk SARM Stack

Moderate-High

The mid-tier SARM physique cycle — RAD-140 drives mass and aggression, LGD-4033 adds density and strength, MK-677 supports recovery, sleep, and connective tissue, with on-cycle enclomiphene to maintain HPTA function and TUDCA for liver protection throughout. Full PCT with both SERMs to fully restart.

12wk5 compoundsPCTView

Tony Huge Dry Aesthetic SARM Stack

High

The hard, dry, vascular SARM stack popularized by Enhanced Athlete — AC-262 as the low-suppression anabolic base, S-23 for that competition-dry hardness, YK-11 for myostatin inhibition and muscle-cell hyperplasia. On-cycle enclomiphene is mandatory because S-23 is heavily suppressive, plus TUDCA for liver throughout.

12wk5 compoundsPCTView

Beachmaxx (Tan + Sex Stack)

Moderate

The complete looksmaxxer beach-prep protocol — Melanotan-1 drives clean melanogenesis without MT-2's nausea/libido side effects, PT-141 (bremelanotide) covers central libido via melanocortin signalling, and tadalafil handles peripheral blood flow via PDE5 inhibition. Tan, desire, and performance — three lanes, zero overlap.

12wk3 compoundsView

Conclusion

This protocol is the reset button for severe acne, chronically oily skin, or textural issues you haven't been able to fix with anything else. Commit to the timeline and adjunct care—by the end you'll have a clean slate and a smoother, healthier baseline for years. If you ever wanted to see what your skin could be at its best, this is how the serious community does it.