IQ MAXXING Stack
Risk: ModerateA precision weekly cycling protocol for maximal cognitive output — Flmodafinil on sprint days (Mon/Wed/Fri) for peak focus and context-switching, Bromantane on recovery days (Tue/Thu/Sat) for dopamine synthesis upregulation, Dihexa + Quercetin Phytosome during 6-week ON cycles for neurotrophin amplification, and a daily foundation covering acetylcholine, neuroprotection, and sleep architecture. Engineered for knowledge workers and developers running at the edge of cognitive capacity.
Composition: 9 Nootropics · 7 Supplements · 2 Longevity
Overview
The IQ MAXXING Stack is engineered for knowledge workers, devs, analysts, and cognitive heavy-hitters who care about raw output, sustained memory, and mental resilience — not just short-term focus boosts. This protocol isn't built for naivety or casual interest: it's the product of deep nootropics and biochemistry research, favoring protocols that layer daily neuroprotection, synaptic plasticity upregulation, acute-dosing stimulants, and periodic cycling of truly novel neurotrophic agents (like dihexa). Every compound is here by design: not 'just because it might help', but because it synergizes with the stack, reduces risk, and is supported by a mature literature or robust community reporting. This is not a lowest-common-denominator, mass-market nootropic blend. If the goal is maximum learn/unlearn/relearn velocity — with recovery and long-term brain health in mind — this is the model protocol.
Why this stack works
- Daily Cognitive Foundation: The stack covers every major pillar the community recognizes as essential for sustained cognitive output — cellular energy (creatine), inflammatory control and myelination (omega-3), endocrine environment (D3+K2), glutathione cycling (NAC, glycine), stress/cortisol management (ashwagandha), hippocampal BDNF and acetylcholine tone (bacopa, magnesium threonate, theanine), and sleep-stage optimization (glycine, apigenin, magnesium threonate). Each is dosed at the range shown to move blood markers or clinical effect — not a sprinkle-formula.
- Flmodafinil Days: Flmodafinil is reserved for structured 'sprint' blocks (Mon/Wed/Fri), using l-tyrosine and CDP-choline to keep catecholamine and acetylcholine pools topped up and blunt the comedown or focus-burnout some users get with repeated psychostimulant class compounds. Acute dopaminergic drive without chronic tolerance.
- Bromantane Days: Bromantane (Tue/Thu/Sat) is slotted as a non-stimulant dopaminergic upregulator, functioning as both a mental recovery tool and proactive anti-tolerance agent to balance stim-heavy days. It upregulates tyrosine hydroxylase, sustaining dopamine over days/weeks — minimizing crash and keeping mood/focus elevated without making every day 'stim' high.
- Dihexa ON Cycle: Dihexa is a textbook synaptogenic (drives neuroplasticity and connective wiring), so it's pulsed for 6 weeks, during the maximum learning/intensity window, backed by quercetin (which acts both as a bioavailability multiplier and as a neuroinflammatory modulator). This is front-loaded (weeks 1–6) to coordinate with ramped mental load or skill-acquisition periods.
- Dihexa OFF / NGF Bridge: Lion's Mane bridges weeks 7–12 post-Dihexa, upregulating NGF/BDNF slower but cleaner, to maintain the neural growth signal while resetting Dihexa-related tolerance, and protect any new wiring laid down in the ON phase. Standard protocol in the community for synaptogenic cycles.
Protocol timeline
5 phases · 12 weeks total
Timeline shows the 12-week cycle. Bars overlap when phases run concurrently. Click a bar to jump to its detail card.
Cycle starts
2025
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
2026
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
2027
Jan
Feb
Mar
Apr
May
Jun
Jul
Aug
Sep
Oct
Nov
Dec
| Week | Compound | Dose | Frequency | Notes |
|---|---|---|---|---|
| 1-12 | Creatine Monohydrate | 5 g | Daily | Increase to 7.5–10 g for high-bulk/veg protocols |
| 1-12 | Omega-3 (EPA+DHA) | 2–4 g | Daily | rTG form preferred; dose by EPA+DHA, not 'fish oil' |
| 1-12 | Vitamin D3 | 5000 IU | Daily | Dose with fat; target 40–60 ng/mL 25(OH)D |
| 1-12 | Vitamin K2 (MK-7) | 180–320 µg | Daily | MK-7 form; avoid concurrent warfarin |
| 1-12 | NAC | 600–1200 mg | Daily | Split AM/PM with food for GI comfort |
| 1-12 | L-Theanine | 100–200 mg | 1–2x/day | AM (stimulant smoothing), PM (sleep) |
| 1-12 | Bacopa (CDRI-08, etc.) | 320–450 mg | Daily | Standardized extract (>50% bacosides), empty stomach |
| 1-12 | Ashwagandha (KSM-66) | 300–600 mg | Daily | AM or PM; continuous use, cycle at 6–12w intervals |
| 1-12 | Magnesium L-Threonate | 2 g (MgT eq) | Daily | PM preferred, split for GI tolerance |
| 1-12 | Glycine | 3–5 g | PM (pre-bed) | Can scale to 10–15 g if also for collagen/joints |
| 1-12 | Apigenin | 50 mg | PM | With fat – sleep and estrogen management |
- High-dose vitamin D3 only with K2 (MK-7) — prevents soft-tissue calcification.
- NAC: separate from raw vitamin C for optimal absorption.
- Glycine and magnesium L-threonate synergize for sleep architecture — pair pre-bed.
- Bacopa: Effective only after 8–12 weeks. No acute nootropic effect; must run consistently.
- Avoid high-dose antioxidants (NAC, vitamin C > 1g) around training if primary goal is neuroplasticity — can blunt adaptation.
| Week | Compound | Dose | Frequency | Notes |
|---|---|---|---|---|
| 1-12 | Flmodafinil | 50–150 mg | 3x/week (Mon/Wed/Fri) | AM only; cut-off after 11am for sleep |
| 1-12 | L-Tyrosine | 500–2000 mg | With Flmodafinil dose | Empty stomach; consider 2x split for bigger sessions |
| 1-12 | CDP-Choline | 200–300 mg | With Flmodafinil dose | Can adjust upward if cognitive load is extreme |
- Flmodafinil AM use only — avoid late-afternoon administration to prevent sleep disruption; stack with L-theanine if excess stimulation/anxiety.
- L-tyrosine: Do not combine with MAOIs or levodopa.
- Choline: Dose CDP-choline on Flmodafinil days to support membrane and acetylcholine turnover.
- Caffeine: If used, halve habitual dose — Flmodafinil synergizes strongly, avoid overstimulation.
| Week | Compound | Dose | Frequency | Notes |
|---|---|---|---|---|
| 1-12 | Bromantane | 50–100 mg | 3x/week (Tue/Thu/Sat) | AM/early PM; do not exceed 400 mg/wk. |
- Bromantane has a subtle anxiolytic edge; use for mental 'recovery days' or focus blocks after heavy stim use.
- Avoid alcohol on Bromantane days (CYP450 interaction risk).
- Long half-life: avoid stacking with other dopaminergic agents on same day.
- Competitive athletes: WADA-banned, long detection windows.
| Week | Compound | Dose | Frequency | Notes |
|---|---|---|---|---|
| 1-6 | Dihexa (oral/sublingual) | 8–16 mg | Daily | Titrate from 8 mg up; cycle max 6w |
| 1-6 | Quercetin (phytosome form) | 250–500 mg | Daily | Lecithin-phytosome form for BBB penetration |
- Start in week 1, end after week 6 — DO NOT continue Dihexa indefinitely (oncogenic pathway concern).
- Quercetin boosts Dihexa CNS bioavailability but is also anti-neuroinflammatory; avoid fluoroquinolone antibiotics and strong CYP3A4 inhibitors.
- Avoid high-dose antioxidants (like NAC) in same AM window if the goal is maximal synaptic plasticity.
- Monitor for headache, odd mood drift, or motor symptoms — rare but worth noting given Dihexa's novel mechanism.
- No Lion's Mane or NGF-mimetic mushrooms during ON phase.
| Week | Compound | Dose | Frequency | Notes |
|---|---|---|---|---|
| 7-12 | Lion's Mane | 1000 mg | Daily | Dual-extract, fruiting body only; empty stomach |
- Begin week 7, after Dihexa ends, to maintain BDNF/NGF signaling during neural consolidation phase.
- Dual-extract, fruiting body Lion's Mane only — avoid mycelium/grain blends (low hericenone/erinacine).
- Continue all base-layer daily foundation compounds.
- Do not combine with Dihexa or any NGF-mimetic drugs.
- Lion's Mane may increase histamine in sensitive subjects — monitor for any unusual allergic, mood, or skin responses.
Compounds in this stack
18 linked · tap for full guide
L-Tyrosine
Catecholamine Precursor
Flmodafinil
Atypical Dopamine Reuptake Inhibitor (Eugeroic)
Magnesium L-Threonate
Brain-Targeted Magnesium Salt
Vitamin K2
Vitamin K-Dependent Carboxylation Cofactor
Glycine
Conditionally Essential Amino Acid
Apigenin
Flavonoid / CD38 Inhibitor
Bacopa Monnieri
Cholinergic / BDNF-Modulating Botanical Nootropic
Lion's Mane
Neurotrophic Mushroom Extract
Bromantane
Actoprotector / Adamantane-class Anxiolytic Stimulant
Citicoline (CDP-Choline)
Cholinergic Precursor
Quercetin
Flavonoid Polyphenol / Senolytic
N-Acetylcysteine
Glutathione Precursor / Antioxidant
Omega-3 (EPA + DHA)
Marine-derived PUFA
Vitamin D3
Secosteroid Prohormone
Ashwagandha
Adaptogen / HPA-axis Modulator
L-Theanine
Glutamate Analog / Anxiolytic Amino Acid
Creatine Monohydrate
Ergogenic Amino Acid Derivative
Dihexa
HGF/c-Met Positive Modulator
How they work together
Multipliers applied to the projection above when these compounds run together. Values > 1 indicate a bonus, < 1 a penalty.
| Pair | Type | Lean | Fat loss | Recovery |
|---|---|---|---|---|
| synergistic | ×1.00 | ×1.08 | ×1.15 | |
| synergistic | ×1.00 | ×1.00 | ×1.18 | |
| synergistic | ×1.00 | ×1.00 | ×1.15 | |
| synergistic | ×1.00 | ×1.00 | ×1.18 |
Cycle outcome projection
Projection across all phases (12 weeks total) using the same math as the stack-calculator tool. Adjust gender, cycle length, and goal to see how the numbers move.
Body Transformation Preview


Lean Mass Gain
3.0 lbs
2.2–3.7 lbs range
Fat Loss
0.0 lbs
0.0–0.0 lbs range
Fat Loss Synergy
+8%
from compound pairing
Per-Compound Contribution
Lean Gain by Week
Where to buy

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Conclusion
This is the protocol for researchers aiming for peak cognition, memory, and sustainable mental output — not just acute 'smart drug' effects. If maximal learning, neuroplasticity, and focus are required for the project's timeline, this stack is the sharpest option. For future refinements and in-depth compound breakdowns, review the per-compound dossiers before each phase transition.
Updated 2026-05-18