IQ MAXXING Stack

Risk: Moderate

A precision weekly cycling protocol for maximal cognitive output — Flmodafinil on sprint days (Mon/Wed/Fri) for peak focus and context-switching, Bromantane on recovery days (Tue/Thu/Sat) for dopamine synthesis upregulation, Dihexa + Quercetin Phytosome during 6-week ON cycles for neurotrophin amplification, and a daily foundation covering acetylcholine, neuroprotection, and sleep architecture. Engineered for knowledge workers and developers running at the edge of cognitive capacity.

12-week cycle5 phases18 compounds
Best forCognition 8/10
Cycle12wk
Compounds18
RiskModerate
9 min read

Composition: 9 Nootropics · 7 Supplements · 2 Longevity

6× Twice daily9× Once daily3× As needed

Overview

The IQ MAXXING Stack is engineered for knowledge workers, devs, analysts, and cognitive heavy-hitters who care about raw output, sustained memory, and mental resilience — not just short-term focus boosts. This protocol isn't built for naivety or casual interest: it's the product of deep nootropics and biochemistry research, favoring protocols that layer daily neuroprotection, synaptic plasticity upregulation, acute-dosing stimulants, and periodic cycling of truly novel neurotrophic agents (like dihexa). Every compound is here by design: not 'just because it might help', but because it synergizes with the stack, reduces risk, and is supported by a mature literature or robust community reporting. This is not a lowest-common-denominator, mass-market nootropic blend. If the goal is maximum learn/unlearn/relearn velocity — with recovery and long-term brain health in mind — this is the model protocol.

Why this stack works

  • Daily Cognitive Foundation: The stack covers every major pillar the community recognizes as essential for sustained cognitive output — cellular energy (creatine), inflammatory control and myelination (omega-3), endocrine environment (D3+K2), glutathione cycling (NAC, glycine), stress/cortisol management (ashwagandha), hippocampal BDNF and acetylcholine tone (bacopa, magnesium threonate, theanine), and sleep-stage optimization (glycine, apigenin, magnesium threonate). Each is dosed at the range shown to move blood markers or clinical effect — not a sprinkle-formula.
  • Flmodafinil Days: Flmodafinil is reserved for structured 'sprint' blocks (Mon/Wed/Fri), using l-tyrosine and CDP-choline to keep catecholamine and acetylcholine pools topped up and blunt the comedown or focus-burnout some users get with repeated psychostimulant class compounds. Acute dopaminergic drive without chronic tolerance.
  • Bromantane Days: Bromantane (Tue/Thu/Sat) is slotted as a non-stimulant dopaminergic upregulator, functioning as both a mental recovery tool and proactive anti-tolerance agent to balance stim-heavy days. It upregulates tyrosine hydroxylase, sustaining dopamine over days/weeks — minimizing crash and keeping mood/focus elevated without making every day 'stim' high.
  • Dihexa ON Cycle: Dihexa is a textbook synaptogenic (drives neuroplasticity and connective wiring), so it's pulsed for 6 weeks, during the maximum learning/intensity window, backed by quercetin (which acts both as a bioavailability multiplier and as a neuroinflammatory modulator). This is front-loaded (weeks 1–6) to coordinate with ramped mental load or skill-acquisition periods.
  • Dihexa OFF / NGF Bridge: Lion's Mane bridges weeks 7–12 post-Dihexa, upregulating NGF/BDNF slower but cleaner, to maintain the neural growth signal while resetting Dihexa-related tolerance, and protect any new wiring laid down in the ON phase. Standard protocol in the community for synaptogenic cycles.

Protocol timeline

5 phases · 12 weeks total

Timeline shows the 12-week cycle. Bars overlap when phases run concurrently. Click a bar to jump to its detail card.

Cycle starts

2025

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

2026

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

2027

Jan

Feb

Mar

Apr

May

Jun

Jul

Aug

Sep

Oct

Nov

Dec

WeekCompoundDoseFrequencyNotes
1-12Creatine Monohydrate5 gDailyIncrease to 7.5–10 g for high-bulk/veg protocols
1-12Omega-3 (EPA+DHA)2–4 gDailyrTG form preferred; dose by EPA+DHA, not 'fish oil'
1-12Vitamin D35000 IUDailyDose with fat; target 40–60 ng/mL 25(OH)D
1-12Vitamin K2 (MK-7)180–320 µgDailyMK-7 form; avoid concurrent warfarin
1-12NAC600–1200 mgDailySplit AM/PM with food for GI comfort
1-12L-Theanine100–200 mg1–2x/dayAM (stimulant smoothing), PM (sleep)
1-12Bacopa (CDRI-08, etc.)320–450 mgDailyStandardized extract (>50% bacosides), empty stomach
1-12Ashwagandha (KSM-66)300–600 mgDailyAM or PM; continuous use, cycle at 6–12w intervals
1-12Magnesium L-Threonate2 g (MgT eq)DailyPM preferred, split for GI tolerance
1-12Glycine3–5 gPM (pre-bed)Can scale to 10–15 g if also for collagen/joints
1-12Apigenin50 mgPMWith fat – sleep and estrogen management
  • High-dose vitamin D3 only with K2 (MK-7) — prevents soft-tissue calcification.
  • NAC: separate from raw vitamin C for optimal absorption.
  • Glycine and magnesium L-threonate synergize for sleep architecture — pair pre-bed.
  • Bacopa: Effective only after 8–12 weeks. No acute nootropic effect; must run consistently.
  • Avoid high-dose antioxidants (NAC, vitamin C > 1g) around training if primary goal is neuroplasticity — can blunt adaptation.
Phase 2
Flmodafinil Days (Mon / Wed / Fri)
mainWk 1–1212wk
WeekCompoundDoseFrequencyNotes
1-12Flmodafinil50–150 mg3x/week (Mon/Wed/Fri)AM only; cut-off after 11am for sleep
1-12L-Tyrosine500–2000 mgWith Flmodafinil doseEmpty stomach; consider 2x split for bigger sessions
1-12CDP-Choline200–300 mgWith Flmodafinil doseCan adjust upward if cognitive load is extreme
  • Flmodafinil AM use only — avoid late-afternoon administration to prevent sleep disruption; stack with L-theanine if excess stimulation/anxiety.
  • L-tyrosine: Do not combine with MAOIs or levodopa.
  • Choline: Dose CDP-choline on Flmodafinil days to support membrane and acetylcholine turnover.
  • Caffeine: If used, halve habitual dose — Flmodafinil synergizes strongly, avoid overstimulation.
Phase 3
Bromantane Days (Tue / Thu / Sat)
mainWk 1–1212wk
WeekCompoundDoseFrequencyNotes
1-12Bromantane50–100 mg3x/week (Tue/Thu/Sat)AM/early PM; do not exceed 400 mg/wk.
  • Bromantane has a subtle anxiolytic edge; use for mental 'recovery days' or focus blocks after heavy stim use.
  • Avoid alcohol on Bromantane days (CYP450 interaction risk).
  • Long half-life: avoid stacking with other dopaminergic agents on same day.
  • Competitive athletes: WADA-banned, long detection windows.
Phase 4
Dihexa ON Cycle (Weeks 1-6)
mainWk 1–66wk
WeekCompoundDoseFrequencyNotes
1-6Dihexa (oral/sublingual)8–16 mgDailyTitrate from 8 mg up; cycle max 6w
1-6Quercetin (phytosome form)250–500 mgDailyLecithin-phytosome form for BBB penetration
  • Start in week 1, end after week 6 — DO NOT continue Dihexa indefinitely (oncogenic pathway concern).
  • Quercetin boosts Dihexa CNS bioavailability but is also anti-neuroinflammatory; avoid fluoroquinolone antibiotics and strong CYP3A4 inhibitors.
  • Avoid high-dose antioxidants (like NAC) in same AM window if the goal is maximal synaptic plasticity.
  • Monitor for headache, odd mood drift, or motor symptoms — rare but worth noting given Dihexa's novel mechanism.
  • No Lion's Mane or NGF-mimetic mushrooms during ON phase.
Phase 5
Dihexa OFF / NGF Bridge (Weeks 7-12)
supportWk 7–126wk
WeekCompoundDoseFrequencyNotes
7-12Lion's Mane1000 mgDailyDual-extract, fruiting body only; empty stomach
  • Begin week 7, after Dihexa ends, to maintain BDNF/NGF signaling during neural consolidation phase.
  • Dual-extract, fruiting body Lion's Mane only — avoid mycelium/grain blends (low hericenone/erinacine).
  • Continue all base-layer daily foundation compounds.
  • Do not combine with Dihexa or any NGF-mimetic drugs.
  • Lion's Mane may increase histamine in sensitive subjects — monitor for any unusual allergic, mood, or skin responses.

Compounds in this stack

18 linked · tap for full guide

L-Tyrosine

Catecholamine Precursor

Nootropic2–3 hoursOral

Flmodafinil

Atypical Dopamine Reuptake Inhibitor (Eugeroic)

Nootropic~10–15 hours (extrapolated; not formally published in humans)OralResearch

Magnesium L-Threonate

Brain-Targeted Magnesium Salt

Nootropic24–48 hours (serum Mg); functional loading curve builds over 1–4 weeksOral

Vitamin K2

Vitamin K-Dependent Carboxylation Cofactor

LongevityMK-7: ~72 hours; MK-4: 1–2 hoursOral

Glycine

Conditionally Essential Amino Acid

Supplement0.5–4 hoursOral

Apigenin

Flavonoid / CD38 Inhibitor

Supplement~2.5 hours (plasma); tissue accumulation extends effective durationOral

Bacopa Monnieri

Cholinergic / BDNF-Modulating Botanical Nootropic

Nootropic3–5 hours (individual bacosides); pharmacodynamic effect builds over weeksOral

Lion's Mane

Neurotrophic Mushroom Extract

NootropicNot established in humansOral

Bromantane

Actoprotector / Adamantane-class Anxiolytic Stimulant

Nootropic~11 hours (oral)OralResearch

Citicoline (CDP-Choline)

Cholinergic Precursor

NootropicBiphasic — choline fraction ~56h, cytidine fraction ~71hOral

Quercetin

Flavonoid Polyphenol / Senolytic

Longevity~11 hours (conjugates, oral)Oral (phytosome)

N-Acetylcysteine

Glutathione Precursor / Antioxidant

Supplement5–6 hoursOral

Omega-3 (EPA + DHA)

Marine-derived PUFA

Supplement~2 days (plasma phospholipid EPA); 3–4 months to plateau RBC membrane incorporationOral

Vitamin D3

Secosteroid Prohormone

Supplement~24h (parent); ~15 days (25-OH-D storage form)Oral

Ashwagandha

Adaptogen / HPA-axis Modulator

Supplement7–10 hours (withanolides, extrapolated)Oral

L-Theanine

Glutamate Analog / Anxiolytic Amino Acid

Nootropic~60 minutesOral

Creatine Monohydrate

Ergogenic Amino Acid Derivative

Supplement~1–1.5 hours (plasma); muscle saturation persists for weeksOral

Dihexa

HGF/c-Met Positive Modulator

Nootropic~10 hours (extrapolated from rat PK; no validated human data)OralResearch

How they work together

Combined effectiveness
Average 0–10 score per dimension across the compounds in this stack (simple mean per axis).
Pairwise synergies

Multipliers applied to the projection above when these compounds run together. Values > 1 indicate a bonus, < 1 a penalty.

PairTypeLeanFat lossRecovery
synergistic×1.00×1.08×1.15
synergistic×1.00×1.00×1.18
synergistic×1.00×1.00×1.15
synergistic×1.00×1.00×1.18

Cycle outcome projection

Projection across all phases (12 weeks total) using the same math as the stack-calculator tool. Adjust gender, cycle length, and goal to see how the numbers move.

Projected Outcomes
Male · 12-week cycle · L-Tyrosine + Flmodafinil + Magnesium L-Threonate + Vitamin K2 + Glycine + Apigenin + Bacopa Monnieri + Lion's Mane + Bromantane + Citicoline (CDP-Choline) + Quercetin + N-Acetylcysteine + Omega-3 (EPA + DHA) + Vitamin D3 + Ashwagandha + L-Theanine + Creatine Monohydrate + Dihexa
12wk

Body Transformation Preview

Average
Very LeanAverageHigh BF
Fit
UntrainedAthleticEnhanced
Before: Fit, Average body fat
BeforeFit · Average BF
After Cycle: Fit & Toned, Average body fat
After CycleFit & Toned · Average BF
+3.0 lb muscleover 12 weeks

Lean Mass Gain

3.0 lbs

2.23.7 lbs range

Fat Loss

0.0 lbs

0.00.0 lbs range

Fat Loss Synergy

+8%

from compound pairing

Per-Compound Contribution

L-TyrosineRecovery / other
FlmodafinilRecovery / other
Magnesium L-ThreonateRecovery / other
Vitamin K2Recovery / other
GlycineRecovery / other
ApigeninRecovery / other
Bacopa MonnieriRecovery / other
Lion's ManeRecovery / other
BromantaneRecovery / other
Citicoline (CDP-Choline)Recovery / other
QuercetinRecovery / other
N-AcetylcysteineRecovery / other
Omega-3 (EPA + DHA)Recovery / other
Vitamin D3Recovery / other
Ashwagandha+0.15 lb lean/wk
L-TheanineRecovery / other
Creatine Monohydrate+0.15 lb lean/wk
DihexaRecovery / other

Lean Gain by Week

Wk 1
0.30 lb
Wk 2
0.29 lb
Wk 3
0.28 lb
Wk 4
0.27 lb
Wk 5
0.26 lb
Wk 6
0.25 lb
Wk 7
0.24 lb
Wk 8
0.23 lb
Wk 9
0.23 lb
Wk 10
0.22 lb
Wk 11
0.21 lb
Wk 12
0.20 lb

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Conclusion

This is the protocol for researchers aiming for peak cognition, memory, and sustainable mental output — not just acute 'smart drug' effects. If maximal learning, neuroplasticity, and focus are required for the project's timeline, this stack is the sharpest option. For future refinements and in-depth compound breakdowns, review the per-compound dossiers before each phase transition.

Updated 2026-05-18