Comparison
LGD-4033 vs RAD-140
Leaner, more predictable gains (LGD) vs. maximum raw power (RAD) — at different risk profiles.
LGD-4033
Selective Androgen Receptor Modulator
RAD-140
Selective Androgen Receptor Modulator
Effectiveness Profile
At a Glance
| LGD-4033 | RAD-140 | |
|---|---|---|
| Type | SARM | SARM |
| Legal status | Research | Research |
| Half-life | 24–36 hours | ~44 hours |
| Preferred route | Oral | Oral |
| Dose frequency | once-daily | once-daily |
| Beginner dose | 5–5 mg | 5–10 mg |
| Intermediate dose | 5–10 mg | 10–20 mg |
| Advanced dose | 10–20 mg | 20–30 mg |
| Cycle length | 6–8 wks | 6–12 wks |
| Bioavailability | 90% | 50% |
| Time to peak | 2h | 1.5h |
| Active duration | 24h | 48h |
| Storage | Room temperature, dry, away from light | Room temperature, dry, away from light. Liquid suspensions stable for 12+ months. |
| PCT required | Yes | Yes |
| Ancillaries required | Yes | Yes |
| Safe for women | No | No |
| Anabolic / androgenic | 500 / 1 | 90 / 1 |
Verdict
LGD-4033 wins for users prioritizing predictable lean mass, a manageable side-effect profile, lower liver stress, and smoother recoverability. Side effects are easier to control, HDL impact is real but generally less severe than RAD's, and standard PCT usually gets you back to baseline.
RAD-140 wins for outright anabolic potency and strength gains, with a muscle-building ceiling that LGD rarely matches. RAD-140 is the oral non-injectable that genuinely mimics low-dose testosterone, with a harder edge and more drive — but it comes with higher HPTA suppression and actual hepatotoxicity risk that demands more frequent bloodwork and careful cycle planning.
Pick A or B?
Pick LGD-4033 if:
- You want steady, reliable lean-mass gains with minimal water retention/hardening
- You're running your first SARM cycle and want a predictable recovery path
- You're stacking with MK-677 or cardarine for a clean recomp or cut
- You need to minimize liver stress (history of elevated enzymes, orals stacking, etc.)
- Hair retention is a key goal (lowest androgenic profile in practice)
Pick RAD-140 if:
- You want maximum anabolic potential and pronounced strength gains from an oral SARM
- You're running a focused strength or mass cycle and are prepared to handle increased suppression 't mind aggressive drive or mood changes during the run
- You tolerate liver stress well (or can monitor with regular bloodwork)
- You need a non-aromatizing, non-5AR substrate and want to avoid hair loss or estrogenic sides from injectables
Where to Buy
Swiss Chems
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- RAD-140· Buy RAD-140 (Testolone), (10mg/capsule) 60 Capsules - SwissChems - Buy Best Quality Peptides, SARMS OnlineBuy RAD-140

NextChems
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- RAD-140· Testolone (RAD-140), 10mg - 60 capsules - Next ChemsBuy RAD-140
- RAD-140· RAD140 Solution, 20mg/ML - 50ML - Next ChemsBuy RAD-140