Comparison
LGD-4033 vs RAD-140
Leaner, more predictable gains (LGD) vs. maximum raw power (RAD) — at different risk profiles.
LGD-4033
Selective Androgen Receptor Modulator
RAD-140
Selective Androgen Receptor Modulator
Effectiveness Profile
At a Glance
| LGD-4033 | RAD-140 | |
|---|---|---|
| Type | SARM | SARM |
| Legal status | Research | Research |
| Half-life | 24–36 hours | ~44 hours |
| Preferred route | Oral | Oral |
| Dose frequency | once-daily | once-daily |
| Beginner dose | 5–5 mg | 5–10 mg |
| Intermediate dose | 5–10 mg | 10–20 mg |
| Advanced dose | 10–20 mg | 20–30 mg |
| Cycle length | 6–8 wks | 6–12 wks |
| Bioavailability | 90% | 50% |
| Time to peak | 2h | 1.5h |
| Active duration | 24h | 48h |
| Storage | Room temperature, dry, away from light | Room temperature, dry, away from light. Liquid suspensions stable for 12+ months. |
| PCT required | Yes | Yes |
| Ancillaries required | Yes | Yes |
| Safe for women | No | No |
| Anabolic / androgenic | 500 / 1 | 90 / 1 |
Verdict
LGD-4033 wins for users prioritizing predictable lean mass, a manageable side-effect profile, lower liver stress, and smoother recoverability. Side effects are easier to control, HDL impact is real but generally less severe than RAD's, and standard PCT usually gets you back to baseline.
RAD-140 wins for outright anabolic potency and strength gains, with a muscle-building ceiling that LGD rarely matches. RAD-140 is the oral non-injectable that genuinely mimics low-dose testosterone, with a harder edge and more drive — but it comes with higher HPTA suppression and actual hepatotoxicity risk that demands more frequent bloodwork and careful cycle planning.
Pick A or B?
Pick LGD-4033 if:
- You want steady, reliable lean-mass gains with minimal water retention/hardening
- You're running your first SARM cycle and want a predictable recovery path
- You're stacking with MK-677 or cardarine for a clean recomp or cut
- You need to minimize liver stress (history of elevated enzymes, orals stacking, etc.)
- Hair retention is a key goal (lowest androgenic profile in practice)
Pick RAD-140 if:
- You want maximum anabolic potential and pronounced strength gains from an oral SARM
- You're running a focused strength or mass cycle and are prepared to handle increased suppression 't mind aggressive drive or mood changes during the run
- You tolerate liver stress well (or can monitor with regular bloodwork)
- You need a non-aromatizing, non-5AR substrate and want to avoid hair loss or estrogenic sides from injectables
Where to Buy
NextChems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy RAD-140 · 10% offRAD-140· Testolone (RAD-140), 10mg - 60 capsules - NextChems
A 9-week protocol at 15 mg/day ≈ 2 bottles
- Buy RAD-140 · 10% offRAD-140· RAD-140 (Testolone) Solution, 20mg/mL – 50mL - NextChems
A 9-week protocol at 15 mg/day ≈ 1 bottle

Swiss Chems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy RAD-140 · 10% offRAD-140· RAD-140 (Testolone), (10mg/capsule) 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 9-week protocol at 15 mg/day ≈ 2 bottles
PCT & Ancillaries
Research protocols built around LGD-4033 typically pair it with PCT and ancillary compounds — these are the ones our partners carry.

Real Peptides
Our pickAffiliate link — we may earn a commission at no cost to you.
20% off — auto-applied at checkout
- Buy Kisspeptin · 20% offKisspeptin· Kisspeptin-10
A 4-week protocol at 150 mcg twice daily ≈ 1 vial
NextChems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy Anastrozole · 10% offAnastrozole· Anastrozole (Arimidex), 0.5mg – 60 Capsules - NextChems
A 10-week protocol at 0.38 mg twice weekly ≈ 1 bottle
- Buy Clomiphene Citrate · 10% offClomiphene Citrate· Clomid (Clomifene / Clomiphene), 25mg – 60 Capsules - NextChems
A 5-week protocol at 37.5 mg/day ≈ 1 bottle
- Buy Enclomiphene Citrate · 10% offEnclomiphene Citrate· Enclomiphene 12.5mg, 60 Capsules - NextChems
A 10-week protocol at 12.5 mg/day ≈ 2 bottles
- Buy Ezetimibe · 10% offEzetimibe· Ezetimibe, 10mg – 60 Capsules - NextChems
A 28-week protocol at 10 mg/day ≈ 4 bottles
- Buy Hydrochlorothiazide · 10% offHydrochlorothiazide· Hydrochlorothiazide (HCTZ), 12.5mg – 60 Capsules - NextChems
A 7-week protocol at 18.75 mg/day ≈ 2 bottles
- Buy Nebivolol · 10% offNebivolol· Nebivolol, 5mg – 60 Capsules - NextChems
A 28-week protocol at 7.5 mg/day ≈ 5 bottles
- Buy Nolvadex · 10% offNolvadex· Tamoxifen (Nolvadex), 20mg – 60 Capsules - NextChems
A 5-week protocol at 30 mg/day ≈ 1 bottle
- Buy Pramipexole · 10% offPramipexole· Pramipexole (Prami), 0.2mg – 60 Capsules - NextChems
A 10-week protocol at 0.19 mg/day ≈ 2 bottles
- Buy Propranolol · 10% offPropranolol· Propranolol, 10mg – 60 Capsules - NextChems
- Buy Raloxifene · 10% offRaloxifene· Raloxifene, 20mg – 60 Capsules - NextChems
A 10-week protocol at 60 mg/day ≈ 4 bottles
- Buy Rosuvastatin · 10% offRosuvastatin· Rosuvastatin, 5mg – 60 Capsules - NextChems
A 28-week protocol at 15 mg/day ≈ 10 bottles
- Buy Telmisartan · 10% offTelmisartan· Telmisartan, 40mg – 60 Capsules - NextChems
A 28-week protocol at 60 mg/day ≈ 5 bottles

Swiss Chems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy Anastrozole · 10% offAnastrozole· Anastrozole (0.5mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 0.38 mg twice weekly ≈ 1 bottle
- Buy Clomiphene Citrate · 10% offClomiphene Citrate· Clomiphene, 1500mg (25mg/capsule) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 5-week protocol at 37.5 mg/day ≈ 1 bottle
- Buy Enclomiphene Citrate · 10% offEnclomiphene Citrate· Enclomiphene (12.5mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 12.5 mg/day ≈ 2 bottles
- Buy Gonadorelin · 10% offGonadorelin· Gonadorelin 2mg - SwissChems-Buy Best Quality Peptides, SARMS Online
A 28-week protocol at 150 mcg/day ≈ 15 vials
- Buy HMG (Human Menopausal Gonadotropin) · 10% offHMG (Human Menopausal Gonadotropin)· HMG 75 IU - SwissChems-Buy Best Quality Peptides, SARMS Online
- Buy Human Chorionic Gonadotropin · 10% offHuman Chorionic Gonadotropin· HCG 5000 IU - SwissChems
- Buy Kisspeptin · 10% offKisspeptin· Kisspeptin-10 10mg - SwissChems-Buy Best Quality Peptides, SARMS Online
A 4-week protocol at 150 mcg twice daily ≈ 1 vial
- Buy Letrozole · 10% offLetrozole· Letrozole (1mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 7-week protocol at 0.88 mg twice weekly ≈ 1 bottle
- Buy Nebivolol · 10% offNebivolol· Nebivolol 300 mg (5 mg / 60 capsules) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 28-week protocol at 7.5 mg/day ≈ 5 bottles
- Buy Nolvadex · 10% offNolvadex· Tamoxifen (20mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 5-week protocol at 30 mg/day ≈ 1 bottle
- Buy Pramipexole · 10% offPramipexole· Pramipexole (Prami), 12 mg (0.2 mg/60 capsules) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 0.19 mg/day ≈ 2 bottles
- Buy Raloxifene · 10% offRaloxifene· Raloxifene (20mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 60 mg/day ≈ 4 bottles
- Buy Telmisartan · 10% offTelmisartan· Telmisartan, 2400mg (40mg/capsule) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 28-week protocol at 60 mg/day ≈ 5 bottles
- Buy Triptorelin · 10% offTriptorelin· GnRH (Triptorelin) 2mg - SwissChems-Buy Best Quality Peptides, SARMS Online