Comparison
AC-262536 vs LGD-4033
AC-262536 brings hair-safe, mild recomp; LGD-4033 brings full-powered lean mass.
AC-262536
Partial Agonist SARM
LGD-4033
Selective Androgen Receptor Modulator
Effectiveness Profile
At a Glance
| AC-262536 | LGD-4033 | |
|---|---|---|
| Type | SARM | SARM |
| Legal status | Research | Research |
| Half-life | ~10–24 hours (inferred, not formally characterized in humans) | 24–36 hours |
| Preferred route | Oral | Oral |
| Dose frequency | once-daily | once-daily |
| Beginner dose | 10–15 mg | 5–5 mg |
| Intermediate dose | 15–20 mg | 5–10 mg |
| Advanced dose | 25–30 mg | 10–20 mg |
| Cycle length | 6–8 wks | 6–8 wks |
| Bioavailability | — | 90% |
| Time to peak | — | 2h |
| Active duration | 24h | 24h |
| Storage | Room temperature, dry, out of direct light | Room temperature, dry, away from light |
| PCT required | Yes | Yes |
| Ancillaries required | No | Yes |
| Safe for women | No | No |
| Anabolic / androgenic | 66 / 27 | 500 / 1 |
Verdict
AC-262536 wins for minimum suppression cycles, hair- and skin-friendliness, and users prioritizing a gentle intro to SARMs or bridges. The partial agonist action and softer anabolic drive mean less stress on HPTA, lipids, and prostate—ideal for long-termers or hair stackers willing to trade peak gains for less risk.
LGD-4033 wins for raw anabolic effect, predictably visible lean-mass gain, and tight dosing protocols for serious bulking or cut-and-hold cycles. It's the higher-impact weapon—more suppression, yes, but also more muscle for the effort, with hard clinical validation behind it and community protocols dialed in for consistent, repeatable results.
Pick A or B?
Pick AC-262536 if:
- You want leaner recomp or bridge periods with minimum endocrine disruption.
- Hair safety (DHT sensitivity, AAS shedding risk) or easier skin is important.
- You're stacking with other hair-safe anabolics or running in a break between harsher cycles.
- First-time SARM users testing the water without risking full shutdown.
- Long-term sustainable use (or stacking with MK-677/Ostarine in milder cycles) is the goal.
Pick LGD-4033 if:
- Your priority is clear, significant lean-mass gain or aggressive body recomposition.
- Short, potent cycles with a defined PCT plan fit your protocol.
- You're experienced with SARMs/AAS and aren't deterred by stronger HPTA suppression.
- Hair loss isn't a primary concern, or you're willing to mitigate via topical antiandrogens.
- You need maximum reliability/effect in a cut, bulk, or even with TRT as a base.
Where to Buy
NextChems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy AC-262536 · 10% offAC-262536· AC-262 (Accadrine), 10mg – 60 Capsules - NextChems
A 7-week protocol at 17.5 mg/day ≈ 2 bottles

Swiss Chems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy AC-262536 · 10% offAC-262536· AC-262 (Accadrine), (10mg/capsule) 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 7-week protocol at 17.5 mg/day ≈ 2 bottles
PCT & Ancillaries
Research protocols built around LGD-4033 typically pair it with PCT and ancillary compounds — these are the ones our partners carry.

Real Peptides
Our pickAffiliate link — we may earn a commission at no cost to you.
20% off — auto-applied at checkout
- Buy Kisspeptin · 20% offKisspeptin· Kisspeptin-10
A 4-week protocol at 150 mcg twice daily ≈ 1 vial
NextChems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy Anastrozole · 10% offAnastrozole· Anastrozole (Arimidex), 0.5mg – 60 Capsules - NextChems
A 10-week protocol at 0.38 mg twice weekly ≈ 1 bottle
- Buy Clomiphene Citrate · 10% offClomiphene Citrate· Clomid (Clomifene / Clomiphene), 25mg – 60 Capsules - NextChems
A 5-week protocol at 37.5 mg/day ≈ 1 bottle
- Buy Enclomiphene Citrate · 10% offEnclomiphene Citrate· Enclomiphene 12.5mg, 60 Capsules - NextChems
A 10-week protocol at 12.5 mg/day ≈ 2 bottles
- Buy Ezetimibe · 10% offEzetimibe· Ezetimibe, 10mg – 60 Capsules - NextChems
A 28-week protocol at 10 mg/day ≈ 4 bottles
- Buy Hydrochlorothiazide · 10% offHydrochlorothiazide· Hydrochlorothiazide (HCTZ), 12.5mg – 60 Capsules - NextChems
A 7-week protocol at 18.75 mg/day ≈ 2 bottles
- Buy Nebivolol · 10% offNebivolol· Nebivolol, 5mg – 60 Capsules - NextChems
A 28-week protocol at 7.5 mg/day ≈ 5 bottles
- Buy Nolvadex · 10% offNolvadex· Tamoxifen (Nolvadex), 20mg – 60 Capsules - NextChems
A 5-week protocol at 30 mg/day ≈ 1 bottle
- Buy Pramipexole · 10% offPramipexole· Pramipexole (Prami), 0.2mg – 60 Capsules - NextChems
A 10-week protocol at 0.19 mg/day ≈ 2 bottles
- Buy Propranolol · 10% offPropranolol· Propranolol, 10mg – 60 Capsules - NextChems
- Buy Raloxifene · 10% offRaloxifene· Raloxifene, 20mg – 60 Capsules - NextChems
A 10-week protocol at 60 mg/day ≈ 4 bottles
- Buy Rosuvastatin · 10% offRosuvastatin· Rosuvastatin, 5mg – 60 Capsules - NextChems
A 28-week protocol at 15 mg/day ≈ 10 bottles
- Buy Telmisartan · 10% offTelmisartan· Telmisartan, 40mg – 60 Capsules - NextChems
A 28-week protocol at 60 mg/day ≈ 5 bottles

Swiss Chems
Affiliate link — we may earn a commission at no cost to you.
10% off — auto-applied at checkout
- Buy Anastrozole · 10% offAnastrozole· Anastrozole (0.5mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 0.38 mg twice weekly ≈ 1 bottle
- Buy Clomiphene Citrate · 10% offClomiphene Citrate· Clomiphene, 1500mg (25mg/capsule) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 5-week protocol at 37.5 mg/day ≈ 1 bottle
- Buy Enclomiphene Citrate · 10% offEnclomiphene Citrate· Enclomiphene (12.5mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 12.5 mg/day ≈ 2 bottles
- Buy Gonadorelin · 10% offGonadorelin· Gonadorelin 2mg - SwissChems-Buy Best Quality Peptides, SARMS Online
A 28-week protocol at 150 mcg/day ≈ 15 vials
- Buy HMG (Human Menopausal Gonadotropin) · 10% offHMG (Human Menopausal Gonadotropin)· HMG 75 IU - SwissChems-Buy Best Quality Peptides, SARMS Online
- Buy Human Chorionic Gonadotropin · 10% offHuman Chorionic Gonadotropin· HCG 5000 IU - SwissChems
- Buy Kisspeptin · 10% offKisspeptin· Kisspeptin-10 10mg - SwissChems-Buy Best Quality Peptides, SARMS Online
A 4-week protocol at 150 mcg twice daily ≈ 1 vial
- Buy Letrozole · 10% offLetrozole· Letrozole (1mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 7-week protocol at 0.88 mg twice weekly ≈ 1 bottle
- Buy Nebivolol · 10% offNebivolol· Nebivolol 300 mg (5 mg / 60 capsules) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 28-week protocol at 7.5 mg/day ≈ 5 bottles
- Buy Nolvadex · 10% offNolvadex· Tamoxifen (20mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 5-week protocol at 30 mg/day ≈ 1 bottle
- Buy Pramipexole · 10% offPramipexole· Pramipexole (Prami), 12 mg (0.2 mg/60 capsules) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 0.19 mg/day ≈ 2 bottles
- Buy Raloxifene · 10% offRaloxifene· Raloxifene (20mg/capsule), 60 Capsules - SwissChems-Buy Best Quality Peptides, SARMS Online
A 10-week protocol at 60 mg/day ≈ 4 bottles
- Buy Telmisartan · 10% offTelmisartan· Telmisartan, 2400mg (40mg/capsule) - SwissChems-Buy Best Quality Peptides, SARMS Online
A 28-week protocol at 60 mg/day ≈ 5 bottles
- Buy Triptorelin · 10% offTriptorelin· GnRH (Triptorelin) 2mg - SwissChems-Buy Best Quality Peptides, SARMS Online