Comparison
Ostarine vs RAD-140
Ostarine is your lean-preservation bridge; RAD-140 is your oral mass-builder.
Ostarine
Selective Androgen Receptor Modulator
RAD-140
Selective Androgen Receptor Modulator
Effectiveness Profile
At a Glance
| Ostarine | RAD-140 | |
|---|---|---|
| Type | SARM | SARM |
| Legal status | Research | Research |
| Half-life | ~24 hours | ~44 hours |
| Preferred route | Oral | Oral |
| Dose frequency | once-daily | once-daily |
| Beginner dose | 10–15 mg | 5–10 mg |
| Intermediate dose | 20–25 mg | 10–20 mg |
| Advanced dose | 25–30 mg | 20–30 mg |
| Cycle length | 8–12 wks | 6–12 wks |
| Bioavailability | 85% | 50% |
| Time to peak | 3h | 1.5h |
| Active duration | 24h | 48h |
| Storage | Room temperature, away from light; liquid suspensions stable for months sealed | Room temperature, dry, away from light. Liquid suspensions stable for 12+ months. |
| PCT required | Yes | Yes |
| Ancillaries required | Yes | Yes |
| Safe for women | Yes | No |
| Anabolic / androgenic | 90 / 30 | 90 / 1 |
Verdict
Ostarine wins for safety, manageable suppression, and lean tissue retention during a cut or recomp. It's the go-to SARM for minimal androgenic sides, predictable results, and low hepatotoxicity when run solo. Most users tolerate it well, even on their first cycle.
RAD-140 wins for raw anabolic potency, scale-moving gains, and oral-only cycles that actually rival low-dose testosterone. It's the SARM people run when they want real growth, serious strength jumps, or to bridge off harsher orals — but it's also notably harsher on liver enzymes and suppression.
Pick A or B?
Pick Ostarine if:
- You want to preserve lean mass on a cut or in a recomp phase without real risk of bulk-induced bloat or fat gain.
- Suppression and side effects are a real concern (first cycle, cautious approach, optimizing for safety/longevity).
- You're stacking SARMs for an aggressive recomp and want an anchor SARM with low androgenic baggage.
- Female users seeking mild anabolic effect with tolerable virilization risk.
- You want to bridge between cycles with a mild, sustainable compound that doesn't hammer the HPTA.
Pick RAD-140 if:
- You want oral-only mass and strength gains that meaningfully rival a low-test cycle (especially if you can't or won't pin).
- Androgenic side effects (acne, hair loss, aggression) are manageable, and your priority is maximum anabolic return per mg.
- You're stacking with ostarine or LGD for a serious recomp or bulk block and want true synergy, not just marginal add-on effect.
- You need a non-aromatizing anabolic that won't wreck the scalp (for finasteride-sensitive users avoiding DHT-based compounds).
- You're prepared to manage real PCT and monitor liver enzymes due to higher suppression/hepatotoxicity profile.
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