Comparison

Human Chorionic Gonadotropin vs HMG (Human Menopausal Gonadotropin)

hCG maintains testicular function on cycle; HMG restores fertility via FSH support.

Effectiveness Profile

Human Chorionic Gonadotropin
HMG (Human Menopausal Gonadotropin)

At a Glance

 Human Chorionic GonadotropinHMG (Human Menopausal Gonadotropin)
TypeAncillary / PCTAncillary / PCT
Legal statusRx-OnlyRx-Only
Half-lifeBiphasic — initial ~6h, terminal ~33hFSH ~24 h; LH ~10–12 h
Preferred routeSubQSubQ
Dose frequencytwice-weeklythree-times-weekly
Beginner dose250–500 IU75–75 IU
Intermediate dose500–1500 IU75–150 IU
Advanced dose1500–3000 IU150–300 IU
Cycle length2–52 wks12–24 wks
Bioavailability100%70%
Time to peak16h9h
Active duration96h48h
StorageLyophilized: room temp stable. Reconstituted: 2–8°C refrigerated, ~30 days (up to 60 if kept cold and stable).Lyophilized vial stored at 2–8°C (or room temp per label); reconstituted solution used immediately or refrigerated short-term
PCT requiredNoNo
Ancillaries requiredYesYes
Safe for womenNoYes

Verdict

Human Chorionic Gonadotropin wins for: On-cycle testicular maintenance, simple PCT kickstarts, rapid bump in intratesticular testosterone, ease of dosing, and lower cost/greater availability. Ideal when LH mimicry alone is sufficient to preserve testicular health and testosterone output.

HMG (Human Menopausal Gonadotropin) wins for: Full-spectrum fertility restoration—especially where spermatogenesis is suppressed after long cycles—as it delivers both FSH (via urinary-derived FSH/LH) and LH activity. HMG is the gold standard for bringing sperm count back up in cases where hCG alone isn't sufficient. Essential for users with FSH-flatlined HPTA or those planning conception after heavy suppression.

Pick A or B?

Pick Human Chorionic Gonadotropin if:

  • You want to maintain testicular size and function while on TRT, cruising, or blasting.
  • Your primary goal is to keep endogenous testosterone and avoid atrophy during suppression.
  • You want a simple PCT kickstart before a SERM run.
  • You're not actively trying to conceive but want to maintain fertility reserves.
  • Cost, convenience, and fewer injections matter to you.

Pick HMG (Human Menopausal Gonadotropin) if:

  • You're actively trying to restore or maximize fertility (spermatogenesis) after long-term suppression.
  • Previous hCG-only protocols haven't brought your sperm count back up.
  • You're running fertility labs and see flatlined FSH despite normal testicular volume.
  • You're stacking with hCG for a full mimetic of pituitary output (LH+FSH).
  • Refractory cases or IVF prep with a timeline for conception.

Where to Buy

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